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Article

The role of Aurora A in hypoxia-inducible factor 1α-promoting malignant phenotypes of hepatocelluar carcinoma.

Cell cycle (Georgetown, Tex.) - 1 Sept 2013

Cui Shi-Yun, Huang Jia-Yuan, Chen Yi-Tian, Song Hai-Zhu, Huang Gui-Chun, De Wei, Wang Rui, Chen Long-Bang

Abstract excerpt

Overexpression of both hypoxia-inducible factor 1α (HIF-1α) and Aurora A has been found in hepatocellular carcinoma (HCC). However, whether HIF-1α and Aurora A synergistically promote malignant phenotypes of HCC cells is unknown. The purpose of this study was to investigate the roles and functional correlation of HIF-1α and Aurora A in HCC progression. Immunohistochemistry was performed to detect HIF-1α and...

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Source

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Identifiers

PMID: 23966163
DOI: 10.4161/cc.25916
PMCID: PMC3899198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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