Article
Significance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC.
BMC cancer - 28 Aug 2010
Lin Zhong-Zhe, Jeng Yung-Ming, Hu Fu-Chang, Pan Hung-Wei, Tsao Hsin-Wei, Lai Po-Lin, Lee Po-Huang, Cheng Ann-Lii, Hsu Hey-Chi
Abstract excerpt
BACKGROUND: To investigate the significance of Aurora B expression in hepatocellular carcinoma (HCC). METHODS: The Aurora B and Aurora A mRNA level was measured in 160 HCCs and the paired nontumorous liver tissues by reverse transcription-polymerase chain reaction. Mutations of the p53 and β-catenin genes were analyzed in 134 and 150 tumors, respectively, by direct sequencing of exon 2 to exon 11 of p53 and exon...
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