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Article

Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults.

Behavior genetics - 1 Sept 2013

Chorlian David B, Rangaswamy Madhavi, Manz Niklas, Wang Jen-Chyong, Dick Danielle, Almasy Laura, Bauer Lance, Bucholz Kathleen, Foroud Tatiana, Hesselbrock Victor, Kang Sun J, Kramer John, Kuperman Sam, Nurnberger John, Rice John, Schuckit Marc, Tischfield Jay, Edenberg Howard J, Goate Alison, Bierut Laura, Porjesz Bernice

Abstract excerpt

Discrete time survival analysis was used to assess the age-specific association of event-related oscillations (EROs) and CHRM2 gene variants on the onset of regular alcohol use and alcohol dependence. The subjects were 2,938 adolescents and young adults ages 12-25. Results showed that the CHRM2 gene variants and ERO risk factors had hazards which varied considerably with age. The bulk of the significant...

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Source

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Identifiers

PMID: 23963516
DOI: 10.1007/s10519-013-9604-z
PMCID: PMC4110722

Genes

CHRM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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