Article
Neurophysiological endophenotypes, CNS disinhibition, and risk for alcohol dependence and related disorders.
TheScientificWorldJournal - 2 Nov 2007
Porjesz Bernice, Rangaswamy Madhavi
Abstract excerpt
Biological endophenotypes are more proximal to gene function than psychiatric diagnosis, providing a powerful strategy in searching for genes in psychiatric disorders. These intermediate phenotypes identify both affected and unaffected members of an affected family, including offspring at risk, providing a more direct connection with underlying biological vulnerability. The Collaborative Study on the Genetics of...
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