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Article

Cholinergic receptor gene (CHRM2) variation and familial loading for alcohol dependence predict childhood developmental trajectories of P300.

Psychiatry research - 30 Oct 2013

Hill Shirley Y, Jones Bobby L, Holmes Brian, Steinhauer Stuart R, Zezza Nicholas, Stiffler Scott

Abstract excerpt

P300 amplitude in childhood predicts substance use disorders by young adulthood. Trajectories of visual P300 amplitude show an association between low amplitude P300 and familial risk for alcohol dependence (AD). Variation in the cholinergic muscarinic receptor gene (CHRM2) has previously been associated with P300 amplitude and AD. The present study used group based trajectory modeling of auditory P300 data...

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Source

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Identifiers

PMID: 23747232
DOI: 10.1016/j.psychres.2013.04.027
PMCID: PMC3796118

Genes

CHRM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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