Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence.

doi:10.1002/ajmg.b.31136

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Article

Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2011

Zlojutro Mark, Manz Niklas, Rangaswamy Madhavi, Xuei Xiaoling, Flury-Wetherill Leah, Koller Daniel, Bierut Laura J, Goate Alison, Hesselbrock Victor, Kuperman Samuel, Nurnberger John, Rice John P, Schuckit Marc A, Foroud Tatiana, Edenberg Howard J, Porjesz Bernice, Almasy Laura

Abstract excerpt

Event-related brain oscillations (EROs) represent highly heritable neuroelectrical correlates of human perception and cognitive performance that exhibit marked deficits in patients with various psychiatric disorders. We report the results of the first genome-wide association study (GWAS) of an ERO endophenotype-frontal theta ERO evoked by visual oddball targets during P300 response in 1,064 unrelated individuals...

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Identifiers

PMID: 21184583
DOI: 10.1002/ajmg.b.31136
PMCID: PMC3139811

Genes

HTR7

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