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Article

Determination of genomic copy number alteration emphasizing a restriction site-based strategy of genome re-sequencing.

Bioinformatics (Oxford, England) - 15 Nov 2013

Zheng Caihong, Miao Xuexia, Li Yanen, Huang Ying, Ruan Jue, Ma Xi, Wang Li, Wu Chung-I, Cai Jun

Abstract excerpt

MOTIVATION: Copy number abbreviation (CNA) is one type of genomic aberration that is often induced by genome instability and is associated with diseases such as cancer. Determination of the genome-wide CNA profile is an important step in identifying the underlying mutation mechanisms. Genomic data based on next-generation sequencing technology are particularly suitable for determination of high-quality CNA...

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PMID: 23962614
DOI: 10.1093/bioinformatics/btt481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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