Article
Two NDR kinase-MOB complexes function as distinct modules during septum formation and tip extension in Neurospora crassa.
Molecular microbiology - 1 Nov 2009
Maerz Sabine, Dettmann Anne, Ziv Carmit, Liu Yi, Valerius Oliver, Yarden Oded, Seiler Stephan
Abstract excerpt
NDR kinases are important for growth and differentiation and require interaction with MOB proteins for activity and function. We characterized the NDR kinases and MOB activators in Neurospora crassa and identified two NDR kinases (COT1 and DBF2) and four MOB proteins (MOB1, MOB2A, MOB2B and MOB3/phocein) that form two functional NDR-MOB protein complexes. The MOB1-DBF2 complex is not only essential for septum...
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