Article
Depletion of Aspergillus nidulans cotA causes a severe polarity defect which is not suppressed by the nuclear migration mutation nudA2.
Molecular genetics and genomics : MGG - 1 Jun 2006
Johns Sarah Anne, Leeder Abigail Claire, Safaie Mehran, Turner Geoffrey
Abstract excerpt
The Aspergillus nidulans homologue of Neurospora crassa cot-1, cotA, encoding a member of the NDR protein kinase family, has been cloned and expressed under the control of the conditional alcA promoter. Depletion of CotA by repression of the alcA promoter led to a severe growth defect accompanied by loss of polarity. Germlings show greatly enlarged volume of the spores and hyphae, accompanied by an increase in...
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