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Article

Influence of cartilage extracellular matrix molecules on cell phenotype and neocartilage formation.

Tissue engineering. Part A - 1 Jan 2014

Grogan Shawn P, Chen Xian, Sovani Sujata, Taniguchi Noboru, Colwell Clifford W, Lotz Martin K, D'Lima Darryl D

Abstract excerpt

Interaction between chondrocytes and the cartilage extracellular matrix (ECM) is essential for maintaining the cartilage's role as a low-friction and load-bearing tissue. In this study, we examined the influence of cartilage zone-specific ECM on human articular chondrocytes (HAC) in two-dimensional and three-dimensional (3D) environments. Two culture systems were used. SYSTEM 1: HAC were cultured on cell-culture...

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Source

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Identifiers

PMID: 23962090
DOI: 10.1089/ten.TEA.2012.0618
PMCID: PMC3875188

Genes

PRG4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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