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Article

Importance of Matrix Cues on Intervertebral Disc Development, Degeneration, and Regeneration

21 Jun 2022

Abstract excerpt

Back pain is one of the leading causes of disability worldwide and is frequently caused by degeneration of the intervertebral discs. The discs' development, homeostasis, and degeneration are driven by a complex series of biochemical and physical extracellular matrix cues produced by and transmitted to native cells. Thus, understanding the roles of different cues is essential for designing effective cellular and...

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PMID: 35805921
DOI: 10.3390/ijms23136915

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