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Article

Human expression QTLs are enriched in signals of environmental adaptation.

Genome biology and evolution - 1 Jan 2013

Ye Kaixiong, Lu Jian, Raj Srilakshmi Madhura, Gu Zhenglong

Abstract excerpt

Expression quantitative trait loci (eQTLs) have been found to be enriched in trait-associated single-nucleotide polymorphisms (SNPs). However, whether eQTLs are adaptive to different environmental factors and its relative evolutionary significance compared with nonsynonymous SNPs (NS SNPs) are still elusive. Compiling environmental correlation data from three studies for more than 500,000 SNPs and 42...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23960253
DOI: 10.1093/gbe/evt124
PMCID: PMC3787676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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