Runt-related transcription factor 3: single nucleotide polymorphism rs760805, gene expression, and methylation status in Helicobacter pylori -infected patients for determination of gastric cancer risk.

doi:10.1007/s12029-013-9540-4

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Article

Runt-related transcription factor 3: single nucleotide polymorphism rs760805, gene expression, and methylation status in Helicobacter pylori -infected patients for determination of gastric cancer risk.

Journal of gastrointestinal cancer - 1 Dec 2013

Nadarajan Nithya, Balasubramanian Lakshman Kumar, Kuppannan Suresh, Ramachandran Chandirasekar, Leelakrishnan Venkatakrishnan

Abstract excerpt

PURPOSE: Repression of Runt-related transcription factor 3 (Runx3) gene, a tumor suppressor, has been known to be involved in Helicobacter pylori (H. pylori)-associated gastric carcinogenesis and cancer development. The present study was undertaken to study the Runx3 intronic T/A polymorphism (rs760805) in H. pylori-infected patients and uninfected controls of Tamil Nadu region, South India. Also, Runx3 gene...

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PMID: 23959374
DOI: 10.1007/s12029-013-9540-4

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