Article
[Cnb1 involved in cytokinesis in Schizosaccharomyces pombe].
Yi chuan = Hereditas - 1 Aug 2013
Fan Jie-Qiong, Deng Xiao-Long, Feng Bi-Wei, Wang Ji-Feng, Yu Yao, Lv Hong
Abstract excerpt
Serine/Threonine-specific calcineurin (CN) is highly conserved in eukaryotes, which plays an important role in transcriptional regulation. In Schizosaccharomyces pombe, CN exists as a heterodimer composed by catalytic subunit Ppb1 and regulatory subunit Cnb1. Deletion of cnb1+ reduced the growth rate of cells, and caused a chained phenotype, and had delay in cytokinesis. In cytokinesis, Cnb1 could form CN complex...
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