Article
Correct regulation of the septation initiation network in Schizosaccharomyces pombe requires the activities of par1 and par2.
Genetics - 1 Aug 2001
Jiang W, Hallberg R L
Abstract excerpt
In Schizosaccharomyces pombe, the initiation of cytokinesis is regulated by a septation initiation network (SIN). We previously reported that deletion of par1 and par2, two S. pombe genes encoding B' regulatory subunits of protein phosphatase 2A, causes a multiseptation phenotype, very similar to that seen in hyperactive SIN mutants. In this study, we examined the genetic interactions between par deletions and...
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