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Article

[Association between six single nucleotide polymorphisms of EGLN1 gene and adaptation to high-altitude hypoxia].

Yi chuan = Hereditas - 1 Aug 2013

Li Qian, Liu Shu-Yuan, Lin Ke-Qin, Sun Hao, Yu Liang, Huang Xiao-Qin, Chu Jia-You, Yang Zhao-Qing

Abstract excerpt

To investigate the association between SNPs located in 5'UTR and intron of prolyl hydroxylase 2 (EGLN1 or PHD2) and adaptation to high-altitude hypoxia, the SNPs (rs2066140, rs2808584, rs2491405, rs2486741, rs2486734 and rs21533646) of EGLN1 gene were genotyped using Sequenom MassArray genotyping system in 152 unrelated healthy Tibetan individuals (3 650 m altitude) and 192 Han (5 00 m altitude), and the...

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Share to Acclimatization
Share to Adaptation, Physiological
Share to Altitude
Share to Altitude Sickness
Share to Genotype
Share to Hypoxia-Inducible Factor-Proline Dioxygenases
Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 23956087
DOI: 10.3724/sp.j.1005.2013.00992

Genes

EGLN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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