Article
[Protamine gene polymorphisms and male infertility].
Zhonghua nan ke xue = National journal of andrology - 1 Dec 2015
Jiang Wei-jun, Zhang Jing, Xia Xin-yi, Xu Hao-qin
Abstract excerpt
Protamine (PRM) is one of the most abundant arginine-rich nucleoproteins in sperm and plays an important role in spermatogenesis. In the late stage of spermatogenesis, the replacement of PRM by histone prompts the closer combination between the nuclear matrix of sperm and nucleoprotein in order for high enrichment and condensation of nuclear chromatin in addition to preventing the sperm genome from mutation...
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