Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chronic Ethanol Consumption Disrupts the Core Molecular Clock and Diurnal Rhythms of Metabolic Genes in the Liver without Affecting the Suprachiasmatic Nucleus

12 Aug 2013

Abstract excerpt

Chronic ethanol consumption disrupts several metabolic pathways including β-oxidation and lipid biosynthesis, facilitating the development of alcoholic fatty liver disease. Many of these same metabolic pathways are directly regulated by cell autonomous circadian clocks, and recent studies suggest that disruption of daily rhythms in metabolism contributes to multiple common cardiometabolic diseases (including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circadian rhythm and melatonin
Share to Diet and metabolism studies
Share to Dietary Effects on Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23951220
DOI: 10.1371/journal.pone.0071684

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chronic Ethanol Consumption Disrupts the Core Molecular Clock and Diurnal Rhythms of Metabolic Genes in the Liver without Affecting the Suprachiasmatic NucleusPMID 23951220Read ↗

Genetic deletion of the circadian clock transcription factor BMAL1 and chronic alcohol consumption differentially alter hepatic glycogen in mice.Semantic proximity Read ↗

Circadian Regulation of Gene Expression and Metabolism in the LiverSemantic proximity Read ↗

Circadian Clock and Liver CancerSemantic proximity Read ↗

Circadian disruption: potential implications in inflammatory and metabolic diseases associated with alcoholSemantic proximity Read ↗

Androgen-mediated Perturbation of the Hepatic Circadian System Through Epigenetic Modulation Promotes NAFLD in PCOS MiceSemantic proximity Read ↗

Time-of-day-dependent variation of the hepatic transcriptome and metabolome is disrupted in non-alcoholic fatty liver disease patientsSemantic proximity Read ↗

Hepatocyte Circadian Clocks Control Cholesterol Metabolism and Protect From Metabolic Dysfunction-Associated Steatohepatitis (MASH)Semantic proximity Read ↗

Metabolic Profile and Lipid Metabolism Phenotype in Mice with Conditional Deletion of Hepatic BMAL1.Semantic proximity Read ↗

Non-alcoholic steatohepatitis disrupts diurnal liver transcriptome rhythms in miceSemantic proximity Read ↗

Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis.Semantic proximity Read ↗

Nonalcoholic Steatohepatitis Disrupts Diurnal Liver Transcriptome Rhythms in MiceSemantic proximity Read ↗

Circadian Rhythms, Metabolism, and Chrononutrition in Rodents and Humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.