Article

Time-of-day-dependent variation of the hepatic transcriptome and metabolome is disrupted in non-alcoholic fatty liver disease patients

2023-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Liver homeostasis is ensured in part by time-of-day-dependent processes, many of them being paced by the molecular circadian clock. Liver functions are compromised in non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH), and clock disruption increases susceptibility to non-alcoholic fatty liver disease (NAFLD) progression in rodent models. We therefore investigated whether t...

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Literature Corpus work: fd7696ea-351c-56a5-bc4e-24760619322e
DOI: 10.1101/2023.04.05.535334

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