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Article

RNAi mediated Tiam1 gene knockdown inhibits invasion of retinoblastoma.

PloS one - 1 Jan 2013

Subramanian Nithya, Navaneethakrishnan Saranya, Biswas Jyotirmay, Kanwar Rupinder K, Kanwar Jagat R, Krishnakumar Subramanian

Abstract excerpt

T lymphoma invasion and metastasis protein (Tiam1) is up-regulated in variety of cancers and its expression level is related to metastatic potential of the type of cancer. Earlier, Tiam1 was shown to be overexpressed in retinoblastoma (RB) and we hypothesized that it was involved in invasiveness...

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Identifiers

PMID: 23950931
DOI: 10.1371/journal.pone.0070422
PMCID: PMC3737373

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23950931-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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