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Knockdown of lncRNA PVT1 inhibits retinoblastoma progression by sponging miR-488-3p

21 Feb 2019

Abstract excerpt

Emerging evidence suggests that long non-coding RNAs (lncRNAs) play a regulatory role in the pathogenesis and progression of retinoblastoma (RB). lncRNA plasmacytoma variant translocation 1 (PVT1) is highly expressed in a plenty of tumors, and is believed to serve as an oncogene. However, the expression, roles, and action mechanisms of PVT1 in the carcinogenesis and progression of RB are still largely unknown. In...

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PMID: 30797143
DOI: 10.1016/j.biopha.2019.108627

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