Article
A polymorphism in the leptin gene promoter is associated with anemia in patients with HIV disease.
Blood - 17 Nov 2011
Vanasse Gary J, Jeong Jee-Yeong, Tate Janet, Bathulapalli Harini, Anderson Damon, Steen Hanno, Fleming Mark, Mattocks Kristin, Telenti Amalio, Fellay Jacques, Justice Amy C, Berliner Nancy
Abstract excerpt
To study factors associated with anemia and its effect on survival in HIV-infected persons treated with modern combined antiretroviral therapy (cART), we characterized the prevalence of anemia in the Veterans Aging Cohort Study (VACS) and used a candidate gene approach to identify proinflammatory gene single nucleotide polymorphisms (SNPs) associated with anemia in HIV disease. The study comprised 1597 HIV(+) and...
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