Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline Mutation in <i>BRCA1</i> or <i>BRCA2</i> and Ten-Year Survival for Women Diagnosed with Epithelial Ovarian Cancer

15 Nov 2014

Abstract excerpt

PURPOSE: To analyze the effect of germline mutations in BRCA1 and BRCA2 on mortality in patients with ovarian cancer up to 10 years after diagnosis. EXPERIMENTAL DESIGN: We used unpublished survival time data for 2,242 patients from two case-control studies and extended survival time data for 4,314 patients from previously reported studies. All participants had been screened for deleterious germline mutations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA gene mutations in cancer
Share to Ovarian cancer diagnosis and treatment
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25398451
DOI: 10.1158/1078-0432.ccr-14-2497

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline Mutation in <i>BRCA1</i> or <i>BRCA2</i> and Ten-Year Survival for Women Diagnosed with Epithelial Ovarian CancerPMID 25398451Read ↗

Association Between <emph type="ital">BRCA1</emph> and <emph type="ital">BRCA2</emph> Mutations and Survival in Women With Invasive Epithelial Ovarian CancerSemantic proximity Read ↗

Effects of BRCA1- and BRCA2-related mutations on ovarian and breast cancer survival: a meta-analysis.Semantic proximity Read ↗

Long-term ovarian cancer survival associated with mutation in BRCA1 or BRCA2.Semantic proximity Read ↗

Effect of BRCA1 and BRCA2 mutations on endometrial carcinoma survival ratesSemantic proximity Read ↗

Family history of cancer and cancer risks in women with BRCA1 or BRCA2 mutations.Semantic proximity Read ↗

Ovarian cancer after breast cancer in women with a BRCA1 or BRCA2 pathogenic variant.Semantic proximity Read ↗

Epidemiology of Patients with Ovarian Cancer with and Without a BRCA1/2 Mutation.Semantic proximity Read ↗

Better life expectancy in women with BRCA2 compared with BRCA1 mutations is attributable to lower frequency and later onset of ovarian cancer.Semantic proximity Read ↗

Improved survival for BRCA2-associated serous ovarian cancer compared with both BRCA-negative and BRCA1-associated serous ovarian cancer.Semantic proximity Read ↗

Association of Genetic Testing Results With Mortality Among Women With Breast Cancer or Ovarian Cancer.Semantic proximity Read ↗

"BRCAness" syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations.Semantic proximity Read ↗

Improved survival in BRCA2 carriers with ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.