Article
The neurogenic response of cardiac resident nestin(+) cells was associated with GAP43 upregulation and abrogated in a setting of type I diabetes.
Cardiovascular diabetology - 12 Aug 2013
Chabot Andreanne, Meus Marc-Andre, Hertig Vanessa, Duquette Natacha, Calderone Angelino
Abstract excerpt
BACKGROUND: Cardiac nestin(+) cells exhibit properties of a neural progenitor/stem cell population characterized by the de novo synthesis of neurofilament-M in response to ischemic injury and 6-hydroxydopamine administration. The induction of growth associated protein 43 (GAP43) was identified as an early event of neurogenesis. The present study tested the hypothesis that the de novo synthesis of neurofilament-M...
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