Article
The plating of rat scar myofibroblasts on matrigel unmasks a novel phenotype; the self assembly of lumen-like structures.
Journal of cellular biochemistry - 1 Jul 2012
El-Helou Viviane, Gosselin Hugues, Villeneuve Louis, Calderone Angelino
Abstract excerpt
During tissue healing, the primary role of myofibroblasts involves the synthesis and deposition of collagen. However, it has also been reported that selective populations of myofibroblasts can acquire the phenotype and/or differentiate to other cells types. The present study tested the hypothesis that myofibroblasts isolated from the scar of the ischemically damaged rat heart can recapitulate an endothelial...
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