Article
Noninvasive monitoring of oxidative stress in transplanted mesenchymal stromal cells.
JACC. Cardiovascular imaging - 1 Jul 2013
Psaltis Peter J, Peterson Karen M, Xu Rende, Franchi Federico, Witt Tyra, Chen Ian Y, Lerman Amir, Simari Robert D, Gambhir Sanjiv S, Rodriguez-Porcel Martin
Abstract excerpt
OBJECTIVES: The goal of this study was to validate a pathway-specific reporter gene that could be used to noninvasively image the oxidative status of progenitor cells. BACKGROUND: In cell therapy studies, reporter gene imaging plays a valuable role in the assessment of cell fate in living subjects. After myocardial injury, noxious stimuli in the host tissue confer oxidative stress to transplanted cells that may...
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