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Article

Nestin (+) stem cells independently contribute to neural remodelling of the ischemic heart.

Journal of cellular physiology - 1 May 2011

Béguin Pauline C, El-Helou Viviane, Gillis Marc-Antoine, Duquette Natacha, Gosselin Hugues, Brugada Ramon, Villeneuve Louis, Lauzier Dominique, Tanguay Jean-Francois, Ribuot Christophe, Calderone Angelino

Abstract excerpt

Recent studies have revealed the existence of multipotent nestin-immunoreactive cells in the adult mammalian heart. These cells were recruited to infarct site following ischemic injury and differentiated to a vascular lineage leading to de novo blood vessel formation. Here, we show that a sub-population of cardiac resident nestin((+)) cells can further differentiate to a neuronal-like fate in vivo following...

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Identifiers

PMID: 20945344
DOI: 10.1002/jcp.22441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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