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Article

Effects of acute dopamine precusor depletion on immediate reward selection bias and working memory depend on catechol-O-methyltransferase genotype.

Journal of cognitive neuroscience - 1 Dec 2013

Kelm Mary Katherine, Boettiger Charlotte A

Abstract excerpt

Little agreement exists as to acute dopamine (DA) manipulation effects on intertemporal choice in humans. We previously found that catechol-O-methyltransferase (COMT) Val158Met genotype predicts individual differences in immediate reward selection bias among adults. Moreover, we and others have shown that the relationship between COMT genotype and immediate reward bias is inverted in adolescents. No previous...

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Identifiers

PMID: 23937688
DOI: 10.1162/jocn_a_00464
PMCID: PMC3816120

Genes

COMT

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Effects of acute dopamine precusor depletion on immediate reward selection bias and working memory depend on catechol-O-methyltransferase genotype.PMID 23937688Read ↗

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Do oral contraceptives affect young women's memory? Dopamine-dependent working memory is influenced by COMT genotype, but not time of pill ingestion.Semantic proximity Read ↗

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