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Article

Tripartite motif‐containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear‐located RING domain†

6 Apr 2009

Abstract excerpt

UNLABELLED: Members of the tripartite motif (TRIM) family are a part of the innate immune system to counter intracellular pathogens. TRIM22 has been reported to possess antiretroviral activity. Here we report that TRIM22 is involved in antiviral immunity against hepatitis B virus (HBV). Our results showed that TRIM22, being a strongly induced gene by interferons in human hepatoma HepG2 cells, could inhibit HBV...

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PMID: 19585648
DOI: 10.1002/hep.23011

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Tripartite motif‐containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear‐located RING domain†PMID 19585648Read ↗

Tripartite motif-containing protein 21 is involved in IFN-γ-induced suppression of hepatitis B virus by regulating hepatocyte nuclear factorsSemantic proximity Read ↗

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Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genesSemantic proximity Read ↗

A 5' extended IFN-stimulating response element is crucial for IFN-gamma-induced tripartite motif 22 expression via interaction with IFN regulatory factor-1.Semantic proximity Read ↗

Suppression of interferon-mediated anti-HBV response by single CpG methylation in the 5′-UTR of TRIM22Semantic proximity Read ↗

E3 ubiquitin ligase TRIM21 restricts hepatitis B virus replication by targeting HBx for proteasomal degradation.Semantic proximity Read ↗

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Comprehensive Analysis of TRIM Family Genes in Hepatitis Virus B-Related Hepatoma CarcinomaSemantic proximity Read ↗

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