Article
The N-terminus of CD14 acts to bind apoptotic cells and confers rapid-tethering capabilities on non-myeloid cells.
PloS one - 1 Jan 2013
Thomas Leanne, Bielemeier Anne, Lambert Peter A, Darveau Richard P, Marshall Lindsay J, Devitt Andrew
Abstract excerpt
Cell death and removal of cell corpses in a timely manner is a key event in both physiological and pathological situations including tissue homeostasis and the resolution of inflammation. Phagocytic clearance of cells dying by apoptosis is a complex sequential process comprising attraction, recognition, tethering, signalling and ultimately phagocytosis and degradation of cell corpses. A wide range of molecules...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
