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Article

Non-motor and motor features in LRRK2 transgenic mice.

PloS one - 1 Jan 2013

Bichler Zoë, Lim Han Chi, Zeng Li, Tan Eng King

Abstract excerpt

BACKGROUND: Non-motor symptoms are increasingly recognized as important features of Parkinson's disease (PD). LRRK2 mutations are common causes of familial and sporadic PD. Non-motor features have not been yet comprehensively evaluated in LRRK2 transgenic mouse models. OBJECTIVE: Using a transgenic mouse model overexpressing the R1441G mutation of the human LRRK2 gene, we have investigated the longitudinal...

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Identifiers

PMID: 23936174
DOI: 10.1371/journal.pone.0070249
PMCID: PMC3728021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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