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Article

Toward repurposing ciclopirox as an antibiotic against drug-resistant Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae.

PloS one - 1 Jan 2013

Carlson-Banning Kimberly M, Chou Andrew, Liu Zhen, Hamill Richard J, Song Yongcheng, Zechiedrich Lynn

Abstract excerpt

Antibiotic-resistant infections caused by gram-negative bacteria are a major healthcare concern. Repurposing drugs circumvents the time and money limitations associated with developing new antimicrobial agents needed to combat these antibiotic-resistant infections. Here we identified the off-patent antifungal agent, ciclopirox, as a candidate to repurpose for antibiotic use. To test the efficacy of ciclopirox...

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Identifiers

PMID: 23936064
DOI: 10.1371/journal.pone.0069646
PMCID: PMC3720592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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