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Leaks in the Pipeline: a Failure Analysis of Gram-Negative Antibiotic Development from 2010 to 2020

26 Apr 2022

Abstract excerpt

The World Health Organization (WHO) has warned that our current arsenal of antibiotics is not innovative enough to face impending infectious diseases, especially those caused by multidrug-resistant Gram-negative pathogens. Although the current preclinical pipeline is well stocked with novel candidates, the last U.S. Food and Drug Administration (FDA)-approved antibiotic with a novel mechanism of action against...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35471042
DOI: 10.1128/aac.00054-22

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