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Article

Repurposing of nucleoside- and nucleobase-derivative drugs as antibiotics and biofilm inhibitors

24 May 2017

Abstract excerpt

There is an urgent need for new antibacterial drugs that are robust against the development of resistance. Drug repurposing is a cost-effective strategy to fast-track the drug development process. Here we examine why the nucleoside and nucleobase analogue drugs in particular present an attractive class for repurposing. Some of these drugs have already been evaluated for their potential as antibacterial agents. In...

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PMID: 28575223
DOI: 10.1093/jac/dkx151

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