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Article

Predicting functionally informative mutations in Escherichia coli BamA using evolutionary covariance analysis.

Genetics - 1 Oct 2013

Dwyer Robert S, Ricci Dante P, Colwell Lucy J, Silhavy Thomas J, Wingreen Ned S

Abstract excerpt

The essential outer membrane β-barrel protein BamA forms a complex with four lipoprotein partners BamBCDE that assembles β-barrel proteins into the outer membrane of Escherichia coli. Detailed genetic studies have shown that BamA cycles through multiple conformations during substrate assembly, su...

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Identifiers

PMID: 23934888
DOI: 10.1534/genetics.113.155861
PMCID: PMC3781972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23934888-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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