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Article

SuperDCA for genome-wide epistasis analysis.

Microbial genomics - 1 Jun 2018

Puranen Santeri, Pesonen Maiju, Pensar Johan, Xu Ying Ying, Lees John A, Bentley Stephen D, Croucher Nicholas J, Corander Jukka

Abstract excerpt

The potential for genome-wide modelling of epistasis has recently surfaced given the possibility of sequencing densely sampled populations and the emerging families of statistical interaction models. Direct coupling analysis (DCA) has previously been shown to yield valuable predictions for single protein structures, and has recently been extended to genome-wide analysis of bacteria, identifying novel interactions...

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Identifiers

PMID: 29813016
DOI: 10.1099/mgen.0.000184
PMCID: PMC6096938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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