Article
ELOVL6 genetic variation is related to insulin sensitivity: a new candidate gene in energy metabolism.
PloS one - 1 Jan 2011
Morcillo Sonsoles, Martín-Núñez Gracia María, Rojo-Martínez Gemma, Almaraz María Cruz, García-Escobar Eva, Mansego María Luisa, de Marco Griselda, Chaves Felipe J, Soriguer Federico
Abstract excerpt
BACKGROUND: The elongase of long chain fatty acids family 6 (ELOVL6) is an enzyme that specifically catalyzes the elongation of saturated and monounsaturated fatty acids with 12, 14 and 16 carbons. ELOVL6 is expressed in lipogenic tissues and it is regulated by sterol regulatory element binding protein 1 (SREBP-1). OBJECTIVE: We investigated whether ELOVL6 genetic variation is associated with insulin sensitivity...
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