Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional significance of the novel H-RAS gene mutation M72I in a patient with medullary thyroid cancer.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Oct 2013

Barollo S, Pezzani R, Cristiani A, Bertazza L, Rubin B, Bulfone A, Pelizzo M R, Torresan F, Mantero F, Pennelli G, Moro S, Mian C

Abstract excerpt

Medullary thyroid cancer (MTC) accounts for around 5-10% of all thyroid cancers. Though usually sporadic, 1 in 4 cases are of genetic origin, with germinal mutations in the RET proto-oncogene in familial forms and somatic mutations both in RET and in the RAS family genes in sporadic ones.This stu...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Medullary
Share to Genes, ras

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Goiter, Nodular

Share to Melanoma

Share to Mitogen-Activated Protein Kinases

Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Mas

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 23934677
DOI: 10.1055/s-0033-1351299

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23934677-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional significance of the novel H-RAS gene mutation M72I in a patient with medullary thyroid cancer.PMID 23934677Read ↗

RET Alterations Differentiate Molecular Profile of Medullary Thyroid Cancer.Semantic proximity Read ↗

Characterization of wild-type and mutated RET proto- oncogene associated with familial medullary thyroid cancer.Semantic proximity Read ↗

Clinical significance of RET and RAS mutations in sporadic medullary thyroid carcinoma: a meta-analysis.Semantic proximity Read ↗

RAS proto-oncogene in medullary thyroid carcinoma.Semantic proximity Read ↗

Identification of potential inhibitor targeting KRAS mutation in Papillary Thyroid Carcinoma through molecular docking and dynamic simulation analysis.Semantic proximity Read ↗

A comprehensive overview of the role of the RET proto-oncogene in thyroid carcinoma.Semantic proximity Read ↗

The RET proto-oncogene in medullary and papillary thyroid carcinoma. Molecular features, pathophysiology and clinical implications.Semantic proximity Read ↗

A New Hot Spot for Mutations in the ret Protooncogene Causing Familial Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Type 2ASemantic proximity Read ↗

Evidence of a Low Prevalence of <i>RAS</i> Mutations in a Large Medullary Thyroid Cancer SeriesSemantic proximity Read ↗

Molecular Mechanisms of RET Activation in Human CancerSemantic proximity Read ↗

Somatic<i>RAS</i>Mutations Occur in a Large Proportion of Sporadic<i>RET</i>-Negative Medullary Thyroid Carcinomas and Extend to a Previously Unidentified ExonSemantic proximity Read ↗

A Historic Perspective and Overview of H-Ras Structure, Oncogenicity, and Targeting.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.