Article
Characterization of wild-type and mutated RET proto- oncogene associated with familial medullary thyroid cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Masbi Mohammad Hosein, Mohammadiasl Javad, Galehdari Hamid, Ahmadzadeh Ahmad, Tabatabaiefar Mohammad Amin, Golchin Neda, Haghpanah Vahid, Rahim Fakher
Abstract excerpt
BACKGROUND: We aimed to assess RET proto-oncogene polymorphisms in three different Iranian families with medullary thyroid cancer (MTC), and performed molecular dynamics simulations and free energy stability analysis of these mutations. MATERIALS AND METHODS: This study consisted of 48 patients and their first-degree relatives with MTC confirmed by pathologic diagnosis and surgery. We performed molecular dynamics...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
