Article
Bayseian genomic models for the incorporation of pathway topology knowledge into association studies.
Statistical applications in genetics and molecular biology - 1 Aug 2013
Brisbin Abra, Fridley Brooke L
Abstract excerpt
Pathway topology and relationships between genes have the potential to provide information for modeling effects of mRNA gene expression on complex traits. For example, researchers may wish to incorporate the prior belief that "hub" genes (genes with many neighbors) are more likely to influence th...
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