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Article

Detection of EGFR mutations in circulating free DNA by PNA-mediated PCR clamping.

Journal of experimental & clinical cancer research : CR - 9 Aug 2013

Kim Hye-Ryoun, Lee Sung Yong, Hyun Dae-Sung, Lee Min Ki, Lee Hyun-Kyung, Choi Chang-Min, Yang Sei-Hoon, Kim Young-Chul, Lee Yong Chul, Kim Sun Young, Jang Seung Hun, Lee Jae Cheol, Lee Kye Young

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR)-activating mutations are major determinants in predicting the tumor response to EGFR tyrosine kinase inhibitors in non-small cell lung cancer (NSCLC). Noninvasive test for the detection of EGFR mutations is required, especially in NSCLC patients from whom tissue is not available. In this study, we assessed the feasibility of detection of EGFR mutations in free...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23927790
DOI: 10.1186/1756-9966-32-50
PMCID: PMC3751150

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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