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Article

Diagnostic value of circulating free DNA for the detection of EGFR mutation status in NSCLC: a systematic review and meta-analysis.

Scientific reports - 9 Sept 2014

Luo Jie, Shen Li, Zheng Di

Abstract excerpt

Epidermal growth factor receptor (EGFR) mutation is a reliable and sensitive biomarker for EGFR-TKI therapy in non-small-cell lung cancer (NSCLC). However, detection of EGFR mutation in tissues has obvious limitations. Circulating free DNA (cfDNA) has been reported as an alternative approach for the detection of EGFR mutations. This systematic review and meta-analysis was designed to assess the diagnostic...

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Area Under Curve
Carcinoma, Non-Small-Cell Lung
ErbB Receptors
Erlotinib Hydrochloride
Gefitinib

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Kinase Inhibitors

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Open in PubMed Open full text

Identifiers

PMID: 25201768
DOI: 10.1038/srep06269
PMCID: PMC5385820

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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