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EGFR T790M Detection in Circulating Tumor DNA from Non-small Cell Lung Cancer Patients Using the PNA-LNA Clamp Method.

Anticancer research - 1 May 2017

Yoshida Hironori, Kim Young Hak, Ozasa Hiroaki, Nagai Hiroki, Sakamori Yuichi, Tsuji Takahiro, Nomizo Takashi, Funazo Tomoko, Yasuda Yuto, Hirai Toyohiro

Abstract excerpt

AIM: To evaluate the utility of plasma circulating tumor DNA (ctDNA) using the peptide nucleic acid-locked nucleic acid (PNA-LNA) clamp method to detect epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) patients who had progressed under treatment with EGFR-tyrosine kinase inhibitors (TKIs). PATIENTS AND METHODS: Blood samples were collected from patients with EGFR...

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PMID: 28476851
DOI: 10.21873/anticanres.11623

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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