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Article

Association of collagen type I alpha 1 gene polymorphism with inguinal hernia.

Hernia : the journal of hernias and abdominal wall surgery - 1 Aug 2014

Sezer S, Şimşek N, Celik H T, Erden G, Ozturk G, Düzgün A P, Çoşkun F, Demircan K

Abstract excerpt

PURPOSE: A positive family history is an important risk factor for inguinal hernia development, suggesting a genetic trait for hernia disease. However, gene mutations responsible for abdominal wall hernia formation in humans have not yet been studied. We aimed to evaluate whether the functional Sp1 binding site polymorphism within intron 1 of the collagen type I, alpha 1 (COL1A1) gene was associated specifically...

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PMID: 23925543
DOI: 10.1007/s10029-013-1147-y

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