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Article

Genetic and biologic risk factors associated with hernia formation: A review.

American journal of surgery - 1 Aug 2024

Amro Chris, Niu Ellen F, Deianni Ellie, Smith Laurie, Qiu Maylene, Torkington Jared, Broach Robyn B, Maguire Lillias H, Damrauer Scott M, Itani Kamal, Fischer John P

Abstract excerpt

BACKGROUND: This systematic review aims to identify genetic and biologic markers associated with abdominal hernia formation. METHODS: Following PRIMSA-guidelines, we searched PubMed, MEDLINE, Embase, Scopus, and COCHRANE databases. RESULTS: Of 5946 studies, 65 were selected, excluding parastomal hernias due to insufficient data. For inguinal hernias, five studies unveiled 92 susceptible loci across 66 genes,...

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PMID: 38519402
DOI: 10.1016/j.amjsurg.2024.02.029

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