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Article

Key role of p63 in BMP-4-Induced Epidermal Commitment of Embryonic Stem Cells

1 Feb 2007

Abstract excerpt

In vivo studies, transgenic and knock-out mice have demonstrated that p63 isoforms play pivotal roles in ectodermal and epidermal development but their respective function remains highly controversial. Since embryonic stem (ES) cells can be differentiated into many cell types, they represent an effective tool to recapitulate in vitro the main steps of embryonic development. We recently reported the efficient...

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PMID: 17264680
DOI: 10.4161/cc.6.3.3800

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