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Article

β-amyloid and ATP-induced diffusional trapping of astrocyte and neuronal metabotropic glutamate type-5 receptors.

Glia - 1 Oct 2013

Shrivastava Amulya Nidhi, Kowalewski Jacob M, Renner Marianne, Bousset Luc, Koulakoff Annette, Melki Ronald, Giaume Christian, Triller Antoine

Abstract excerpt

β-Amyloid (Aβ) oligomers initiate synaptotoxicity following their interaction with the plasma membrane. Several proteins including metabotropic glutamate type 5 receptors (mGluR5s) contribute to this process. We observed an overexpression of mGluR5s in reactive astrocytes surrounding Aβ plaques i...

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Identifiers

PMID: 23922225
DOI: 10.1002/glia.22548

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23922225-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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