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Article

Pills of PTEN? In and out for tumor suppression.

Cell research - 1 Oct 2013

Papa Antonella, Chen Ming, Pandolfi Pier Paolo

Abstract excerpt

The tumor-suppressive activity of PTEN has always been attributed to its endogenous intracellular function. Recently two different groups have demonstrated that PTEN is secreted/exported into the extracellular environment for uptake by recipient cells, and functions as a tumor suppressor in a cell non-autonomous manner.

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Topics

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Share to Exosomes
Share to Gene Expression Regulation, Neoplastic
Share to PTEN gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to PTEN Phosphohydrolase

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Share to Tumor Suppressor Proteins

Source

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Identifiers

PMID: 23917528
DOI: 10.1038/cr.2013.103
PMCID: PMC3790232

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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