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Article

Tango7 directs cellular remodeling by the Drosophila apoptosome.

Genes & development - 1 Aug 2013

D'Brot Alejandro, Chen Po, Vaishnav Mahesh, Yuan Shujun, Akey Christopher W, Abrams John M

Abstract excerpt

It is now well appreciated that the apoptosome, which governs caspase-dependent cell death, also drives nonapoptotic caspase activation to remodel cells. However, the determinants that specify whether the apoptosome acts to kill or remodel have yet to be identified. Here we report that Tango7 collaborates with the Drosophila apoptosome to drive a caspase-dependent remodeling process needed to resolve individual...

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Identifiers

PMID: 23913920
DOI: 10.1101/gad.219287.113
PMCID: PMC3744723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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