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It takes two (centrioles) to tango

29 Nov 2018

Abstract excerpt

Cells that divide during embryo development require precisely two centrioles during interphase and four centrioles during mitosis. This precise number is maintained by allowing each centriole to nucleate only one centriole per cell cycle (i.e. centriole duplication). Yet, how the first cell of the embryo, the zygote, obtains two centrioles has remained a mystery in most mammals and insects. The mystery arose...

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PMID: 30496124
DOI: 10.1530/rep-18-0350

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